Hemp & Cannabis Resources

Benefits of CBD For Pain Management

According to the U.S. Department of Heath & Human Services, studies have shown CBD to be effective in treating neuropathic pain.

You can buy CBD vape pen cartridges at HealthSmart CBD today to start enjoying the potential benefits of Cannabidiol.

CBD For Neuropathic Pain
The therapeutic potential of cannabinoids has been the topic of extensive investigation following the discovery of cannabinoid receptors and their endogenous ligands.

Cannabinoid receptors and their endogenous ligands are present at supraspinal, spinal and peripheral levels.

Cannabinoids suppress behavioral responses to noxious stimulation and suppress nociceptive processing through activation of cannabinoid CB1 and CB2 receptor subtypes.

Endocannabinoids, the brain’s own cannabis-like substances, share the same molecular target as Δ9-tetrahydrocannabinol, the main psychoactive component in cannabis.

Endocannabinoids serve as synaptic circuit breakers and regulate multiple physiological and pathological conditions, e.g. regulation of food intake, immunomodulation, inflammation, analgesia, cancer, addictive behavior, epilepsy and others. This review will focus on uncovering the roles of anandamide (AEA) and 2-arachidonoylglycerol (2-AG), the two best characterized endocannabinoids identified to date, in controlling nociceptive responding.

Effects of modulation of endocannabinoid levels through inhibition of endocannabinoid hydrolysis and uptake is also compared with effects of exogenous administration of synthetic endocannabinoids in acute, inflammatory and neuropathic pain models.

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US Government Patent On Cannabinoids

The U.S. government issued a patent (#6,630,507) for the use of cannabinoids as antioxidants and neuroprotectants way back in October of 2003. That patent was backed by the research of Nobel Prize winning biochemist Julius Axelrod.

 

US Patent #6,630,507 – Cannabinoids as antioxidants and neuroprotectants – The United States of America as represented by the Department of Health and Human Services

 

Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention.

 

It is an object of this invention to provide a new class of antioxidant drugs, that have particular application as neuroprotectants, although they are generally useful in the treatment of many oxidation associated diseases.

 

Yet another object of the invention is to provide a subset of such drugs that can be substantially free of psychoactive or psychotoxic effects, are substantially non-toxic even at very high doses, and have good tissue penetration, for example crossing the blood brain barrier.

 

It has surprisingly been found that cannabidiol and other cannabinoids can function as neuroprotectants, even though they lack NMDA receptor antagonist activity. This discovery was made possible because of the inventor’s recognition of a previously unanticipated antioxidant property of the cannabinoids in general (and cannabidiol in particular) that functions completely independently of antagonism at the NMDA, AMPA and kainate receptors. Hence the present invention includes methods of preventing or treating diseases caused by oxidative stress, such as neuronal hypoxia, by administering a prophylactic or therapeutically effective amount of a cannabinoid to a subject who has a disease caused by oxidative stress.

 

Souce: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6630507.PN.&OS=PN/6630507&RS=PN/6630507

Pro Cannabis Pro Sports

Medical Marijuana For Professional Athletes and The Role Of Cannabis in Professional Sports

 

Should players in the National Football League and other professional and college sports be allowed to used CBD or other forms of cannabis? It is a questions with many considerations that could have significant implications for thousands of athletes around the world.

In particular we can focus on the sport of football first because the entire sport is facing an existential crisis with the horrors of CTE (chronic traumatic encephalopathy) being linked to concussions from playing football.

If there was a pill that could protect the brain, reduce pain and inflammation, while  reducing stress and anxiety, that would obviously be something the league would be in favor of, right? Uh, well, no. Not exactly. Not at all actually.

In another move that has become typical of the NFL players have been banned from using CBD even though there is no psychoactive effect, and there is no concern of performance enhancement.

This is despite the fact that CBD has been proven repeatedly to act as a significant neuroprotectant and inflammatory agent, and despite the common knowledge that the US Government via the US Department of Health & Human Services owns more than 5 US Patents on Cannabinoids as Neuroprotectants.

At the same time the league is happy to continue prescribing and dispensing pharmaceutical opioid-based pain killer medications for players that have proven to be highly addictive with dramatically negative side effects.

The opioid epidemic has been declared a national emergency and the game of football is doing nothing to help that situation. As a platform with an audience of millions, the league could make a huge impact on public perception by showing the benefits of cannabidiol and allowing players to benefit freely from the natural cure that most of them already use anyway.

Instead, only a few players are singled out and have their careers ruined to make a point in the opposite direction.

The approach in the National Basketball Association seems much more player friendly and the players have been known to benefit greatly from the natural medicinal effects of cannabis for decades without the strict penalties and testing applied against the players in the NFL.

Let us know your thoughts below in the comments… Should NFL and NBA players be allowed to use cannabis and/or CBD?

If you would like to check out some cannabidiol products, we recommend vapor cartridges or disposable pens or a CBD oil tincture if you don’t like vape products. Vaping gives a more instantaneous experience that has a shorter timeframe while the oral/sublingual tincture take a little longer to set in but also lasts a lot longer! We recommend HealthSmart CBD as our number one choice for high quality non-synthetic, whole plant hemp derived CBD products.